Outcome of the Pregnancies after Uterine Cervix Conization

Constant rise of incidence of intraepithelial uterine cervix lesions in young patients implies a larger number of therapeutic surgical procedures. The paper aims to assess the risk of such surgical procedures on later pregnancy and delivery. The paper is a retrospective study performed at the Clinic of Gynecology and Obstetrics in Niš. The study enrolled 30 pregnant women in the experimental group with conization of the uterine cervix in their history, and 90 pregnant women without history data on previously performed conizations. The investigation demonstrated a significantly higher percentage of deliveries before 37 week of gestation in our experimental group – 20% vs 5.5% in the control group. Deliveries in experimental group more commonly started with preterm rupture of membranes (pPROM) – in 13.3% while the corresponding percentage in control group was only 2.22%. Related to operative completion of delivery with cesarean section, there were no significant differences between the groups (6.6% vs 3.3% in experimental and control group, respectively). There was a statistically significant difference in cervix injury during labour in experimental (10%) compared to control group (1.1%). Uterine cervix conization represents a risk for preterm labour in late pregnancy. In these women, delivery more commonly starts with preterm rupture of membranes and uterine cervix injuries are more common. Therefore, conization should be utilized only if strictly indicated in young patients, and those with conization should be closely monitored.